NURS 6052 Evidence-Based Project Part 1 Identifying Research MethodologiesPlease be mindful of plagi

Matrix Worksheet – Evidence-Based Project, Part 1: Identifying Research Methodologies Example Solution

Student’s name

Walden University

Course

Instruction

Month, Day, Year

Matrix Worksheet

Evidence-based practice (EBP) uses clinical inquiry to acquire evidence-based answers to improve practice. In this matrix worksheet, I will compare the various research articles that I selected from a literature search following a clinical inquiry. My clinical issue of interest was gastrointestinal upset after the use of antibiotics and other acute disorders. Antibiotics especially the broad-spectrum ones kill several types of bacteria in the gut and the system. This can lead to eradication or reduction in the normal flora of the gastrointestinal tract.

The reduction of this natural source of defense in the gut can lead to the proliferation and virulence of pathogenic bacteria. Probiotics are exogenous regimens either containing commensals or their substrates that maintain the normal flora in the body (Wang et al., 2020). This clinical inquiry aims at assessing the benefit of prophylactic administration of probiotic foods to prevent gastrointestinal effects of antibiotics used on the gut such as gastrointestinal upset.

My PICOT question stated: “Among patients with gastrointestinal retiled to microbial infections (P), does the use of probiotic foods (I) confer health benefits in improving their health (O) after 3 months (T)?” Several sources were searched and the following four articles were sued to provide evidence-based answers to the clinical questions.

Conclusion

The use of probiotics is not a new concept. However, as health research advances new strains are introduced in the commercial probiotics. This begs the need to ascertain their benefits through evidence-based practice. This matrix comparison analyzed the methodologies of four articles obtained through a literature search using PICOT clinical inquiry. Two studies were randomized control trials, one was a retrospective case-control study, and the other was a pilot control trial study. All studies were quantitative.

NURS 6052 Evidence-Based Project Part 1 Identifying Research Methodologies References

Arnold, L. E., Luna, R. A., Williams, K., Chan, J., Parker, R. A., Wu, Q., Hollway, J. A., Jeffs, A., Lu, F., Coury, D. L., Hayes, C., & Savidge, T. (2019). Probiotics for gastrointestinal symptoms and quality of life in autism: A placebo-controlled pilot trial. Journal of Child and Adolescent Psychopharmacology, 29(9), 659–669. https://doi.org/10.1089/cap.2018.0156

Hibberd, A. A., Yde, C. C., Ziegler, M. L., Honoré, A. H., Saarinen, M. T., Lahtinen, S., Stahl, B., Jensen, H. M., & Stenman, L. K. (2019). Probiotic or synbiotic alters the gut microbiota and metabolism in a randomized controlled trial of weight management in overweight adults. Beneficial Microbes, 10(2), 121–135. https://doi.org/10.3920/BM2018.0028

Melnyk, B. M., & Fineout-Overholt, E. (2018). Evidence-based practice in nursing & healthcare: A guide to best practice (4th ed.). Lippincott Williams and Wilkins.

Rui, X., & Ma, S.-X. (2020). A retrospective study of probiotics for the treatment of children with antibiotic-associated diarrhea. Medicine, 99(23), e20631. https://doi.org/10.1097/MD.0000000000020631

Skrzyd?o-Radoma?ska, B., Prozorow-Król, B., Cicho?-Lach, H., Majsiak, E., Bier?a, J. B., Kanarek, E., Sowi?ska, A., & Cukrowska, B. (2021). The effectiveness and safety of multi-strain probiotic preparation in patients with diarrhea-predominant irritable bowel syndrome: A randomized controlled study. Nutrients, 13(3), 756. https://doi.org/10.3390/nu13030756

Wang, Y., Jiang, Y., Deng, Y., Yi, C., Wang, Y., Ding, M., Liu, J., Jin, X., Shen, L., He, Y., Wu, X., Chen, X., Sun, C., Zheng, M., Zhang, R., Ye, H., An, H., & Wong, A. (2020). Probiotic supplements: Hope or hype? Frontiers in Microbiology, 11, 160. https://doi.org/10.3389/fmicb.2020.00160

NURS 6052 Evidence-Based Project, Part 2: Advanced Levels of Clinical Inquiry and Systematic Reviews

Please be mindful of plagiarism and APA format, I have included the rubric as directed. Please use my course resources as one of my references as instructed. Please include Melnyk, B. M., & Fineout-Overholt, E. (2018). Evidence-based practice in nursing & healthcare: A guide to best practice (4th ed.). Philadelphia, PA: Wolters Kluwer in the references. Thank you.

Your quest to purchase a new car begins with an identification of the factors important to you. As you conduct a search of cars that rate high on those factors, you collect evidence and try to understand the extent of that evidence. A report that suggests a certain make and model of automobile has high mileage is encouraging. But who produced that report? How valid is it? How was the data collected, and what was the sample size?

In this Assignment, you will delve deeper into clinical inquiry by closely examining your PICO(T) question. You also begin to analyze the evidence you have collected.

To Prepare:

Review the Resources and identify a clinical issue of interest that can form the basis of a clinical inquiry.

Develop a PICO(T) question to address the clinical issue of interest you identified in Module 2 for the Assignment. This PICOT question will remain the same for the entire course.

Use the key words from the PICO(T) question you developed and search at least four different databases in the Walden Library. Identify at least four relevant systematic reviews or other filtered high-level evidence, which includes meta-analyses, critically-appraised topics (evidence syntheses), critically-appraised individual articles (article synopses). The evidence will not necessarily address all the elements of your PICO(T) question, so select the most important concepts to search and find the best evidence available.

Reflect on the process of creating a PICO(T) question and searching for peer-reviewed research.

Include a title page, an introduction, and a summary.

My clinical issue of interest was gastrointestinal upset after the use of antibiotics and other acute disorders.

PICOT Question: Why does the use of antibiotics to treat acute disorders lead to gastrointestinal upset among adult patients than when using other medications?

I need 7 slides of PowerPoint presentation.
Please follow the instructions and answer all the required questions.

NURS 6052 Evidence-Based Project, Part 3: Critical Appraisal of Research

Please be mindful of plagiarism and APA format, I have included the rubric as directed and a template. Please use my course-required readings materials for the references.

Assignment: Evidence-Based Project, Part 3: Critical Appraisal of Research

Realtors rely on detailed property appraisals conducted using appraisal tools to assign market values to houses and other properties. These values are then presented to buyers and sellers to set prices and initiate offers.

Research appraisal is not that different. The critical appraisal process utilizes formal appraisal tools to assess the results of research to determine value to the context at hand. Evidence-based practitioners often present these findings to make the case for specific courses of action.

In this Assignment, you will use an appraisal tool to conduct a critical appraisal of published research. You will then present the results of your efforts.

To Prepare:

Reflect on the four peer-reviewed articles you selected in Module 2 and the four systematic reviews (or other filtered high- level evidence) you selected in Module 3.
Reflect on the four peer-reviewed articles you selected in Module 2 and analyzed in Module 3.
Review and download the Critical Appraisal Tool Worksheet Template provided in the Resources.

The Assignment (Evidence-Based Project)

Part 3A: Critical Appraisal of Research

Conduct a critical appraisal of the four peer-reviewed articles you selected by completing the Evaluation Table within the Critical Appraisal Tool Worksheet Template. Choose a total of four peer- reviewed articles that you selected related to your clinical topic of interest in Module 2 and Module 3.

Note: You can choose any combination of articles from Modules 2 and 3 for your Critical Appraisal. For example, you may choose two unfiltered research articles from Module 2 and two filtered research articles (systematic reviews) from Module 3 or one article from Module 2 and three articles from Module 3. You can choose any combination of articles from the prior Module Assignments as long as both modules and types of studies are represented.

Part 3B: Critical Appraisal of Research

Based on your appraisal, in a 1-2-page critical appraisal, suggest a best practice that emerges from the research you reviewed. Briefly explain the best practice, justifying your proposal with APA citations of the research.
Include a title page, an introduction and a summary.

NOTE:
I HAVE ATTACHED THE ARTICLE USED FOR MODULE 2 AND 3. PLEASE USE THE REQUIRED READING FOR THE REFERENCES.
LET ME KNOW IF YOU NEED ACCESS TO WALDEN LIBRARY.

Module 2 Articles

Module 3:

Four articles were selected from the systematic search. The first article, by Nasiri et al. (2018) was a systematic review and metanalyses of randomized control trials thus level I evidence. The second article by Agamennone et al. (2018) is also a systematic review and metanalysis of various clinical studies thus level I evidence. The third article displayed is by Goodman et al. (2021) provides level I evidence because it is from a systematic review and metanalysis study. The fourth article, by Cai et al. (2018) was also a systematic review with network metanalysis thus level I evidence.

Critical Appraisal Tool Worksheet Template  

Evaluation Table